CHALLENGE
Altzheimer and Parkinson Disease
$1 MILLION (Prize amount to be confirmed. Announcement expected for next year)
Alzheimer’s disease is a neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60–70% of cases of dementia.
Parkinson’s disease is a progressive nervous system disorder that affects movement.
Altzheimer, Parkinson and several other diseses ALS, Hungtinton etc are neurodegenerative diseases that affects the brain and have a long pathway with seriously helping continuous progress till the final outcome.
They are mostly caused by the gradual death of individual neurons and supporting glia leading to serious reduction in movement control, memory, cognition, mood and personlity alterations, including impairment in basic motor such as individual ability to carry out basic functions as walking or swallowing.
Also involved in Altzheimer is the lose of synapses which is highly related to cognitive decline. Promising biotechnology based approaches include transplantation of stem cells (considered to seriously helping lerning and memory in older mice models with Altzheimer).
Workdwide there are 35.5 M people with Altzheimer and such number will grow to 116M by 2050 including costs in the order of several hundred billions per year. For such reasons neurodegenerative diseases are important and new ways to deal with them must be researched.