Altzheimer and Parkinson Disease

CHALLENGE

Altzheimer and Parkinson Disease

$1 MILLION (Prize amount to be confirmed. Announcement expected for next year)

Alzheimer’s disease  is a neurodegenerative disease that usually starts slowly and gradually worsens over time. It is the cause of 60–70% of cases of dementia.

Parkinson’s disease is a progressive nervous system disorder that affects movement.

Altzheimer, Parkinson and several other diseses ALS, Hungtinton etc are neurodegenerative diseases that affects the brain and have a long pathway with seriously helping continuous progress till the final outcome.

They are mostly caused by the gradual death of individual neurons and supporting glia leading to serious reduction in movement control, memory, cognition, mood and personlity alterations, including impairment in basic motor such as individual ability to carry out basic functions as walking or swallowing.

Also involved in Altzheimer is the lose of synapses which is highly related to cognitive decline. Promising biotechnology based approaches include transplantation of stem cells (considered to seriously helping lerning and memory in older mice models with Altzheimer).

Workdwide there are 35.5 M people with Altzheimer and such number will grow to 116M by 2050 including costs in the order of several hundred billions per year. For such reasons neurodegenerative diseases are important and new ways to deal with them must be researched.

ALTZHEIMER AND PARKINSON DISEASE

The solution can include:

This competition focuses on early detection methods for the disease and delaying of the disease progression.

The winning team is expected to develop a system for effectively screen patients at risk for Altzheimer disease and will also have to demonstrate the ability to improve cognitive functions in late state Altzheimer patients.

Proposal:

There is full freedom to propose any type of alternative and solution to reach our ultimate goal: to obtain successfull neurodegenerative disease treatments.

Proposals shall consist of a written part, maximum 40 pages , and images , diagrams or charts needed to visualize the concepts proposed (max. 8 images) in pdf.